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Tun Giap Tan

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Articles

Real-World 12 and 18-Month Outcomes of Faricimab in Patients Previously Treated for Neovascular Age-Related Macular Degeneration

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By Tun Giap Tan, Radua Kamal-Salah, Olayinka Osoba
| preprints.org
You are already at the latest version Age-related macular degeneration (nAMD) is a significant cause of visual impairment globally.1 This single-centre retrospective study evaluated real-world outcomes of faricimab in patients with neovascular age-related macular degeneration (nAMD) who responded suboptimally to other anti-VEGF treatment. Patients with nAMD who were switched to faricimab between September and December 2022 with a minimum of 12 months’ follow-up were included.
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Variants in NR6A1 cause a novel oculo vertebral renal syndrome - Nature Communications

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By Uma M Neelathi, Ehsan Ullah, Aman George, Elangovan Boobalan, Chloe Adams, Yuri V. Sergeev, Amelia Naik, Tun Giap Tan, Siying Lin, Gavin Arno, Rodrigo M Young
| Nature Verified
Abstract Colobomatous microphthalmia is a potentially blinding congenital ocular malformation that can present either in isolation or together with other syndromic features. Despite a strong genetic component to disease, many cases lack a molecular diagnosis. We describe an autosomal dominant oculo-vertebral-renal (OVR) syndrome in six independent families characterized by colobomatous microphthalmia, missing vertebrae and congenital kidney abnormalities.
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