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Tycho E. T. Mevissen on Muck Rack

Tycho E. T. Mevissen

As seen in: Cell Press
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Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets

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By Dennis Flierman, Reggy Ekkebus, Paul P. Geurink, Tycho E. T. Mevissen
| Cell Press Verified
S1-S2 Site-Targeting diUb Probes and Substrates Reveal New Insights into OTUD2 Linkage Specificity   An S2 Ub-Binding Site in the OTU Domain of OTUD3 Confers Specificity for K11 Linkages We decided to focus on OTUD2, also known as Yod1, a member of the OTU DUB family, to validate these S1-S2 site-targeting probes.
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