Walk in Brent Sandidge’s shoes, and it’s easy to understand why disease remains one of the biggest concerns facing pork producers today. Three years ago, Ham Hill Farms near Marshall, Mo., was just getting over Porcine Reproductive and Respiratory Syndrome (PRRS) when poor market conditions hit — 2023 was the worst year for profitability on record, even topping 1998, according to economists. “We didn’t have quite the production and then prices were horrible,” Sandidge says.