Uihwan Kim

You are already at the latest version Background: Although tryptophanyl-tRNA synthetase (WRS) is a novel biomarker released during bacterial and viral infections, its prognostic value in sepsis has rarely been reported. We aimed to investigate the prognostic value of WRS in patients with sepsis in the emergency department (ED). Methods: This prospective, observational study included 243 patients with sepsis. Blood samples were collected to measure full-length WRS levels.

1. Introduction Pathological conditions can result in acute hyperglycemia. For example, acute pancreatitis can not only impair glucose metabolism [] but can also induce endothelial injury and dysregulation of vasomotor tone due to inflammatory reactions [].

1. Introduction Blood vessels play an essential role in the homeostatic regulation of peripheral vascular resistance through changes in lumen diameter which, in turn, is controlled by factors that promote vascular constriction or relaxation [1]. Vascular constriction or relaxation (i.e., vascular tone) is mainly influenced by alterations in the cytosolic free calcium (Ca2+) concentration [2] and also by changes in membrane potential [3].