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Articles

Nectin-4 reduces T cell effector function and is a therapeutic target in pancreatic cancer

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By Max Heiduk, Sarah Cronjaeger, Emily A. Kawaler, Ulrich Sommer
| tu-dresden.de
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis and current therapies show limited efficacy. Ligands and receptors of the TIGIT axis were analyzed using multicolor flow cytometry of tumor and blood samples, immunohistochemistry from primary tumors, and single-cell RNA sequencing from primary tumors and liver metastasis from patients with various stages of PDAC. The effect of soluble and plate-bound Nectin-4 on T cell function was tested in vitro.
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A rare case of pancreatic endometriosis in a postmenopausal woman and review of the literature

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By Ulrich Sommer, Gustavo B Baretton, Daniela Aust, Verena Plodeck
| tu-dresden.de
Abstract External IDs PubMedCentral PMC5040200
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JCM | Free Full-Text | Adverse Events with Hypoglossal Nerve Stimulation in the Treatment of Obstructive Sleep Apnea-A Systematic Review of Clinical Trials and Real-World Data

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By Clemens Heiser, Ulrich Sommer, Christoph Schöbel, Mathias Wollny
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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