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Multiscale Synchronization in Beta Cell Networks: Connecting Cellular Oscillations to Hormone Secretion
Affiliations & Notes 1Faculty of Natural Sciences and Mathematics, University of Maribor, Koroška cesta 160, Maribor, 2000, Slovenia 2Faculty of Medicine, University of Maribor, Taborska ulica 8, Maribor, 2000, Slovenia 3University Alma Mater Europaea, Slovenska ulica 17, Maribor, 2000, Slovenia Article Info Publication History: Received May 30, 2026; Accepted August 14, 2026; Published online August 18, 2026 DOI: 10.1016/j.bpj.2026.08.013 External LinkAlso available on ScienceDirect External...
Aging transitions of multimodal oscillators in multilayer networks
When individual oscillators age and become inactive, the collective dynamics of coupled oscillators is often affected as well. Depending on the fraction of inactive oscillators or cascading failures that percolate from crucial information exchange points, the critical shift toward macroscopic inactivity in coupled oscillator networks is known as the aging transition.
Phys. Rev. E 108, 054409 (2023) - Both electrical and metabolic coupling shape the collective multimodal activity and functional connectivity patterns in beta cell collectives: A computational model perspective
Pancreatic beta cells are coupled excitable oscillators that synchronize their activity via different communication pathways. Their oscillatory activity manifests itself on multiple timescales and consists of bursting electrical activity, subsequent oscillations in the intracellular Ca2+, as well as oscillations in metabolism and exocytosis.
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