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Urpu Salmenniemi

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Articles

Impact of conditioning regimen on outcomes of young AML patients ( < 40 years) undergoing HCT in complete remission, with transplant conditioning intensity score of 3.5-4.0. A study from the acute leukemia working party of the European Society for Blood a

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By Enrico Maffini, Maud Ngoya, Mohamed Nabil Houhou, Malek Benakli, Mahmoud Aljurf, Khalid Halahleh, Regis de Latour, Igor-Wolfgang Blau, Andrew Clark, Catherine Flynn, Péter Reményi, Ibrahim Yakoub-Agha, Henrik Sengeloev, Cristina Castilla-Llorente, Emma Nicholson, Urpu Salmenniemi, Radovan Vrhovac, Jakob Passweg, Matthias Eder, Etienne Daguindau, Alexandros Spyridonidis, Arnon Nagler, Fabio Ciceri, Mohamad Mohty Verified, Babak Bahar, Maria Losa Maroto
| Nature Verified
Abstract The optimal myeloablative conditioning regimen for adolescents and young adults with acute myeloid leukaemia (AML) is currently unknown. In this retrospective analysis conducted on AML patients aged 18-40 years, in complete remission (CR), who received an allogeneic hematopoietic cell transplantation (HCT) we compared outcomes of different conditioning regimens.
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Outcomes of 544 Patients with t(6;9)/DEK::NUP214 acute myeloid leukemia undergoing allogeneic stem cell transplantation: an EBMT study on behalf of the acute leukemia working party (ALWP) and the pediatric diseases working party (PDWP)

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By Fabio Andreozzi, Jacques-Emmanuel Galimard, Johan Maertens, Mahmoud Aljurf, Katherine Clesham, Jaime Sanz, Sébastien Maury, Jakob Passweg, Thomas Schroeder, Urpu Salmenniemi, Gwendolyn van Gorkom, Regis de Latour, Franco Locatelli, Robert F. Wynn, Jean-Hugues Dalle, Jordi Esteve, Arnon Nagler, Katharina Kleinschmidt, Mohamad Mohty Verified, Krzysztof Kalwak, Fabio Ciceri, Sandrine Loron, Peter A. von dem Borne
| Nature Verified
Abstract Acute myeloid leukemia (AML) with translocation (6;9)(p23;q34) is a rare and high-risk disease, frequently co-occurring with FLT3-ITD alteration. We retrospectively analyzed 544 patients with t(6;9) AML undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) and reported to the EBMT registry, between 2000 and 2022.
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Influence of invasive aspergillosis during acute leukaemia treatment on survival after allogeneic stem cell transplantation: a prospective study of the EBMT Infectious Diseases Working Party

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By Olaf Penack, Gloria Tridello, Urpu Salmenniemi, Rodrigo Martino
| EClinicalMedicine Verified
Summary Infections are the main reason for mortality during acute leukaemia treatment and invasive aspergillosis (IA) is a major concern. Allogeneic stem cell transplantation (alloSCT) is a standard therapy and often is the only live-saving procedure in leukaemia patients. The profound immunodeficiency occurring after alloSCT led to high IA-associated mortality in the past. Therefore, patients with IA were historically considered transplant-ineligible.
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