Frédéric Baron
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Secondary autoimmune and inflammatory diseases after allogeneic hematopoietic stem cell transplantation: a retrospective study from the EBMT transplant complications and autoimmune diseases working parties
Abstract Secondary autoimmune and inflammatory diseases (SAIDs) are underrecognized and poorly described after allogeneic hematopoietic stem cell transplantation (allo-HSCT). The standardization of management is hindered by the scarcity of data on epidemiology, pathogenesis, and clinical outcomes.
Length of SARS-CoV-2 shedding in HCT recipients: an Infectious Disease Working Party of EBMT study - Bone Marrow Transplantation
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COVID-19 has been associated with increased morbidity and mortality in immunocompromised patients due to inadequate control of the virus, resulting in higher risk of progression to severe disease, clinical and virological relapses and long time to viral elimination [1, 2]. Prolonged shedding of SARS-CoV-2 can also lead to delays in treatment of the underlying disease and viral evolution with the development of resistance [3,4,5].
By Malgorzata Mikulska, Gloria Tridello, Per Ljungman, Jan Styczynski, Diana Averbuch, Simone Cesaro, Nina Knelange, José Luis Piñana, Marina Popova, Nicolaus Kröger, Henrik Sengeloev, Caroline Besley, Hélène Labussiere-Wallet, Zeynep Yegin, Raffaella Greco, Frédéric Baron, Ipek Yonal-Hindilerden, Aliénor Xhaard, Elisabetta Metafuni, Jennifer Byrne, Selami Koçak Toprak, Anna Grassi, Daniele Vallisa, Jennifer Clay, Rodrigo Martino Bufarull, Gwendolyn van Gorkom, Omur Gokmen Sevindik, Keith Wilson, Lotus Wendel, Mareike Verbeek, Rafael de la Camara
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Nature
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Frequency and impact of somatic co-occurring mutations on post-transplant outcomes in acute myeloid leukemia: a multicenter registry analysis on behalf of the EBMT ALWP | Bone Marrow Transplantation
Abstract Acute myeloid leukemia (AML) includes genetically defined subsets. In allogeneic hematopoietic cell transplantation (allo-HCT), the frequency and prognosis of gene-gene interactions may differ from those of patients treated with chemotherapy alone. In this study, adult patients (N = 952) with AML allografted between 2015 and 2023, with available next generation sequencing (NGS) at diagnosis were included.
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