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Articles by Van Cutsem E
Apatinib Plus Toripalimab (Anti-PD1 Therapy) as Second-Line Therapy in Patients With Advanced Gastric or Esophagogastric Junction Cancer: Results From a Randomized, Open-Label Phase II Study
Apatinib, a selective tyrosine kinase inhibitor for vascular endothelial growth factor receptor 2 (VEGFR2), is commonly used as a third-line treatment for patients with GC and has been authorized by the China Food and Drug Administration. Clinical studies have shown that combining immunotherapy with apatinib yields favorable antitumor activity and manageable safety.
Efficacy and Safety of Trifluridine/Tipiracil-Containing Combinations in Colorectal Cancer and Other Advanced Solid Tumors: A Systematic Review
Fluoropyrimidines, including 5-fluorouracil and capecitabine, alone or as part of combination regimens, have formed the mainstay in treating gastrointestinal cancers.1,2 However, resistance to fluoropyrimidines remains a considerable barrier to effective treatment.2 Trifluridine/tipiracil (FTD/TPI or TAS-102; Taiho Oncology, Inc., Princeton, NJ, USA) is an oral cytotoxic agent comprising trifluridine, a thymidine analog, and tipiracil, a thymidine phosphorylase inhibitor.3 FTD/TPI has a...
Association between different types of preoperative anemia and tumor characteristics, systemic inflammation, and survival in colorectal cancer
Throughout the electronic medical record, 95 patients who received surgical treatment in our hospital from February 2016 to January 2018 were chosen according to the inclusion criteria: (1) Patients who were diagnosed with CRC for the first time and underwent radical surgery; (2) pathologically confirmed as CRC; (3) patients who received the relevant index test within one week before the operation; (4) there are relatively complete clinical data and follow-up related information; exclusion...
Wild-Type KRAS Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
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Pharmacokinetic drug-drug interactions with direct anticoagulants in the management of cancer-associated thrombosis
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18F-Labeled Somatostatin Analogs as PET Tracers for the Somatostatin Receptor: Ready for Clinical Use
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Pembrolizumab for previously treated, microsatellite instability-high/mismatch repair-deficient advanced colorectal cancer: final analysis of KEYNOTE-164 - PubMed
doi: 10.1016/j.ejca.2023.02.016. Online ahead of print. Affiliations Affiliations 1 Oncology, Sidney Kimmel Comprehensive Cancer Center at John Hopkins University, Baltimore, MD, USA. Electronic address: dle@jhmi.edu. 2 Medical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Oncology, Asan Medical Center, Seoul, Republic of Korea. 3 Oncology, Asan Medical Center, Seoul, Republic of Korea; University of Ulsan, Ulsan, Republic of Korea.
Trastuzumab deruxtecan in patients in the USA and Europe with HER2-positive advanced gastric or gastroesophageal junction cancer with disease progression on or after a trastuzumab-containing regimen (DESTINY-Gastric02): primary and updated analyses from a
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Prospective comparison of [18F]AlF-NOTA-octreotide PET/MRI to [68Ga]Ga-DOTATATE PET/CT in neuroendocrine tumor patients
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Therapeutic yield of extensive molecular profiling in cholangiocarcinoma: a retrospective single-center study
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Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study - PubMed
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