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Varadh Piamthai on Muck Rack

Varadh Piamthai

As seen in: Cell Reports
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Articles

Mobilization of vitamin B12 transporters alters competitive dynamics in a human gut microbe

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By Ansel Hsiao, Patrick H. Degnan, Katie A. Frye, Varadh Piamthai
| Cell Reports Verified
Highlights • Diverse mobile genetic elements in gut microbes encode vitamin B12 transporters • Transfer of CTns with B12 transporters complement transport-deficient strains • CTns with B12 transporters offer competitive advantages during in vitro growth • In vivo conjugation restores ability to use B12 in transport-deficient Bacteroides Summary The functional and genomic diversity of the human gut microbiome is shaped by horizontal transfer of mobile genetic elements (MGEs).
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