Vasilije P. Tadic

1. Introduction Contextual fear conditioning (CFC) is a form of Pavlovian learning in which an association is made between non-threatening environmental stimuli and painful, dangerous, or threatening stimulation [1,2]. Studies of Pavlovian fear conditioning and extinction in rodents and humans have suggested that a neural circuit including the hippocampus, amygdala, and medial prefrontal cortex is involved in the learning and memory processes that enable context-dependent behavior [3].