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Ved Prakash Verma on Muck Rack

Ved Prakash Verma

As seen in: ScienceDirect, ACS Publications
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Articles

Synthesis of Marine-Inspired Multifaceted DNA Damaging Spirooxindoles Combating NSCLC and Associated Bacterial Infection

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By Mohammad Shahidul Islam, Assem Barakat, Matti Haukka, Ved Prakash Verma
| ACS Publications
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Structure-activity relationship of dual inhibitors containing maleimide and imidazole motifs against glutaminyl cyclase and glycogen synthase kinase-3β

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By Mitsuyasu Kawaguchi, Hidehiko Nakagawa, Akriti Kumari, Ved Prakash Verma
| ScienceDirect Verified
Alzheimer’s disease (AD) is a major cause of dementia and one of the most common chronic diseases affecting the aging population. Because AD is considered a public health priority, there is a critical need to discover novel and effective agents for the treatment of this condition.
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Structure-based development of novel substrate-type G9a inhibitors as epigenetic modulators for sickle cell disease treatment

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By Toshifumi Tatsumi, Motomu Kanai, Akriti Kumari, Ved Prakash Verma
| ScienceDirect Verified
Structure-based development of novel substrate-type G9a inhibitors as epigenetic modulators for sickle cell disease treatment The discovery and development of structurally distinct lysine methyltransferase G9a inhibitors have been the subject of intense research in epigenetics. Structure-based optimization was conducted, starting with the previously reported seed compound 7a and lead to the identification of a highly potent G9a inhibitor, compound 7i (IC = 0.024 μM).
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