Vigneshwarr Muruga Boopathy on Muck Rack

Vigneshwarr Muruga Boopathy

As seen in: Nature
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Dissecting the enhancer gene regulatory network in early Drosophila spermatogenesis - Nature Communications

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By Kerem Yildirim, Tim Lange, Laura Zoe Kreplin, Qian Wang, Katrin Domsch, Anniek Stokkermans, aakriti singh, Josephine Bageritz, Pallavi Santhi Sekhar, Vigneshwarr Muruga Boopathy, Kim Dammer, Shubhanshu Pandey, Xuefan Gao
| Nature
Abstract Cellular decision-making and tissue homeostasis are governed by transcriptional networks shaped by chromatin accessibility. Using single-nucleus multi-omics, we jointly profile gene expression and chromatin accessibility in 10,335 cells from the Drosophila testis apical tip. This enables inference of 147 cell type-specific enhancer-gene regulons using SCENIC + .
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