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Vijay Avin BR on Muck Rack

Vijay Avin BR

As seen in: BioRxiv
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Articles

Endothelial ERG programs neutrophil transcriptome for sustained anti-inflammatory vascular niche

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By Vigneshwaran Vellingiri, Vijay Avin BR, Jagdish Joshi, Zahid Akhter
| BioRxiv
Abstract Neutrophils (PMNs) reside as a marginated pool within the vasculature, ready for deployment during infection. However, how endothelial cells (ECs) control PMN extravasation and activation to strengthen tissue homeostasis remains ill -defined. Here, we found that the vascular ETS-related gene (ERG) is a generalized mechanism regulating PMN activity in preclinical tissue injury models and human patients.
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