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Virginia Barone

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Articles

J. Imaging | Free Full-Text | Integrated Ultrasound Characterization of the Diet-Induced Obesity (DIO) Model in Young Adult c57bl/6j Mice: Assessment of Cardiovascular, Renal and Hepatic Changes

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By Sara Gargiulo, Virginia Barone, Denise Bonente, Tiziana Tamborrino
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Integrated Ultrasound Characterization of the Diet-Induced Obesity (Dio) Model in Young Adult C57bl/6j Mice: Assessment of Cardiovascular, Renal and Hepatic Changes

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By Sara Gargiulo, Virginia Barone, Denise Bonente, Tiziana Tamborrino
| Preprints.org
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 10 July 2024 / Approved: 11 July 2024 / Online: 12 July 2024 (04:09:05 CEST) Gargiulo, S.; Barone, V.; Bonente, D.; Tamborrino, T.; Inzalaco, G.; Gherardini, L.; Bertelli, E.; Chiariello, M. Integrated Ultrasound Characterization of the Diet-Induced Obesity (Dio) Model in Young Adult C57bl/6j Mice: Assessment of Cardiovascular, Renal and Hepatic Changes. Preprints 2024, 2024070987.
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Loco-regional treatment with temozolomide-loaded thermogels prevents glioblastoma recurrences in orthotopic human xenograft models - Scientific Reports

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By Mirko Maturi, Erica Locatelli, Silvia Tortorella, Mauro Comes Franchini, Lisa Gherardini, Giovanni Inzalaco, Sara Gargiulo, Virginia Barone, Lorenzo Franci
| Nature Verified
Abstract Glioblastoma multiforme (GBM) is the most aggressive primary tumor of the central nervous system and the diagnosis is often dismal. GBM pharmacological treatment is strongly limited by its intracranial location beyond the blood–brain barrier (BBB). While Temozolomide (TMZ) exhibits the best clinical performance, still less than 20% crosses the BBB, therefore requiring administration of very high doses with resulting unnecessary systemic side effects.
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