Vita Majce on Muck Rack

Vita Majce

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Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine

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By Sarah Batson, Cesira de Chiara, Adrian Lloyd, Vita Majce
| Nature
E. coli DdlB (EcDdlB) was co-crystallized, as described in methods, with ATP and D-Ala-D-Ala (Fig. 1a), ADP and D-Ala-D-Ala (Fig. 1b), and ATP and DCS (Fig. 1c) and structures determined at sub 2?Å resolution as summarized in Table 1. The overall structure is described in Supplementary Fig 2.
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