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Waitman K. Aumann on Muck Rack

Waitman K. Aumann

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Articles

Fusion of the CRM1 nuclear export receptor to AF10 causes leukemia and transcriptional activation of HOXA genes

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By Jessica Heath, Daniel S. Wechsler, Waitman K. Aumann, Sei-Gyung Kim Sze
| Nature Verified
Fig. 1: CRM1-AF10 and CRM1Δ-AF10 display leukemogenic activity. Fig. 2: Impairing the NUP214/CRM1 interaction abrogates leukemia development. References 1. Kumon K, Kobayashi H, Maseki N, Sakashita A, Sakurai M, Tanizawa A, et al. Mixed-lineage leukemia with t(10;11)(p13;q21): an analysis of AF10-CALM and CALM-AF10 fusion mRNAs and clinical features. Genes Chromosomes Cancer. 1999;25:33–9. CAS Article Google Scholar 2. Dik WA, Brahim W, Braun C, Asnafi V, Dastugue N, Bernard OA, et al.
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