Wangjialu Lu on Muck Rack

Wangjialu Lu

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Articles

Perirhinal cortex gains control of hippocampal seizures via broad downstream circuits in male mouse models

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By Zhisheng Li, Yuhao Sun, Jing Xi, Jialu Chen, Yuying Shao, Fan Fei, Zhong Chen, Yi Wang, Wangjialu Lu, Nanxi Lai
| Nature Verified
Abstract The perirhinal cortex (PRh) has extensive interconnections with limbic structures, including the fasciola cinerea (FC), a recently identified node and therapeutic target in temporal lobe epilepsy. However, the neural circuit basis between PRh and FC in seizure progression remains unclear. Here we show that the PRh provides the principal excitatory input to the FC and plays an important role in seizure modulation in male mouse epilepsy models.
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