Yuying Shao
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Perirhinal cortex gains control of hippocampal seizures via broad downstream circuits in male mouse models
Abstract The perirhinal cortex (PRh) has extensive interconnections with limbic structures, including the fasciola cinerea (FC), a recently identified node and therapeutic target in temporal lobe epilepsy. However, the neural circuit basis between PRh and FC in seizure progression remains unclear. Here we show that the PRh provides the principal excitatory input to the FC and plays an important role in seizure modulation in male mouse epilepsy models.
Astrocytic H3 receptors regulate anxiety through GABA signaling
Keywords astrocyte histamine H3 receptors GABA anxiety disorders Get full text access Log in, subscribe or purchase for full access. References 1. Calhoon, G.G. ∙ Tye, K.M. Resolving the neural circuits of anxiety Nat. Neurosci. 2015; 18:1394-1404 2. Akiki, T.J. ∙ Jubeir, J. ∙ Bertrand, C. ... Neural circuit basis of pathological anxiety Nat. Rev. Neurosci. 2025; 26:5-22 3. Okonogi, T. ∙ Kuga, N. ∙ Yamakawa, M. ...
Subicular Astrocytes Govern Seizure‐Impaired Fear Memory
1 Introduction Epilepsy is one of the most common and disabling brain disorders, affecting ≈1% of the population of all ages.
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