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Articles by Wanjun Lu
CLIC4 inhibits the progression of non-small cell lung cancer by suppressing the MAPK pathway
Abstract In addition to its involvement in maintaining membrane electrical balance, ion homeostasis, and transmembrane transport, intracellular chloride channel protein 4 (CLIC4) is regulated by signaling molecules such as TGF-β, P53, Myc, and TNFα and is closely associated with apoptosis. Nevertheless, the expression patterns and functional roles of CLIC4 across different cancer types remain inconsistent and are not fully understood.
Intrapleural dual blockade of IL-6 and PD-L1 reprograms CAF dynamics and the tumor microenvironment in lung cancer-associated malignant pleural effusion | Respiratory Research | Full Text
A total of 26 lung cancer patients were included in this study, comprising 18 males (69.2%) and 8 females (30.8%) with a median age of 56 years (Supplementary Table 1). Among these, 24 patients (92.3%) were diagnosed with lung adenocarcinoma (LUAD), one (3.8%) with lung squamous cell carcinoma (LUSC), and one (3.8%) with small cell lung cancer (SCLC). Analysis revealed that IL-6 concentrations were significantly higher in MPE compared with serum from the same patients (Supplementary Fig.
Nicotinic acetylcholine receptor modulator insecticides act on diverse receptor subtypes with distinct subunit compositions
Loading metrics Open Access Peer-reviewed Research Article Wanjun Lu , Zhihan Liu , Xinyu Fan , Xinzhong Zhang , Xiaomu Qiao, Jia Huang Wanjun Lu, Zhihan Liu, Xinyu Fan, Xinzhong Zhang, Xiaomu Qiao, Jia Huang Published: January 19, 2022 https://doi.org/10.1371/journal.pgen.1009920 Figures Abstract Insect nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated ion channels mainly expressed in the central nervous system of insects.
PaO 2 /FiO 2 and IL-6 are risk factors of mortality for intensive care COVID-19 patients
Abstract To identify the risk factors of mortality for the coronavirus disease 19 (COVID-19) patients admitted to intensive care units (ICUs) through a retrospective analysis. The demographic, clinical, laboratory, and chest imaging data of patients admitted to the ICU of Huoshenshan Hospital from February 10 to April 10, 2020 were retrospectively analyzed. Student's t-test and Chi-square test were used to compare the continuous and categorical variables, respectively.
Methane Hydration‐Shell Structure and Fragility
As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re‐organized for online delivery, but are not copy‐edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors.
Methane Hydration‐Shell Structure and Fragility
As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re‐organized for online delivery, but are not copy‐edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors.
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