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Xinying Li

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Articles

Hepatocyte Hedgehog activation attenuates acetaminophen-induced liver injury through a Vegfa-associated vascular response

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By Xue Ding, Xinying Li, Zheng Pan, Jinyuan Liang, Xiaoling Jin, Yang Wang, Zheng Zhang, Miao Lu, Ping Mi
| Nature Verified
Abstract Acetaminophen (APAP) overdose is the leading cause of drug-induced acute liver failure, yet early pathways linking hepatocellular stress to tissue integrity remain incompletely defined. Here, we demonstrate that canonical Hh signaling is rapidly activated in centrilobular hepatocytes upon APAP challenge, preceding significant inflammation and recovery.
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Ibuprofen Modulates Tissue-Specific Proteomic Signatures of LPS-Induced Inflammaging in Mice

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By Xinyu Wu, Jianping Zhou, Xinying Li
| Preprints.org
You are already at the latest version Chronic low grade inflammation ("inflammaging") is epidemiologically linked to organ specific aging, but tissue resolved proteomic evidence remains limited. In this exploratory study, we used 4D DIA proteomics to profile heart, liver, spleen, and kidney from mice given chronic LPS (0.1 µg/day i.p., 2 months) with or without ibuprofen co treatment (0.02 mg/mL in drinking water).
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AFDM-enabled, photonics-aided fiber-wireless fronthaul system for integrated sensing and communication

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By Xiang Xin, Hengxin Yan, Xinying Li, Liye Fang
| Optica Verified
Integrated sensing and communication (ISAC) has been widely recognized as a cornerstone of sixth-generation (6G) networks. The prevalence of doubly dispersive channels (DSCs) in high-mobility and high-frequency scenarios has emerged as a critical bottleneck for 6G networks. Affine frequency division multiplexing (AFDM), capable of attaining full diversity gain even in DSC environments, has become a compelling candidate for next-generation ISAC waveforms.
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