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Intrapleural dual blockade of IL-6 and PD-L1 reprograms CAF dynamics and the tumor microenvironment in lung cancer-associated malignant pleural effusion | Respiratory Research | Full Text
A total of 26 lung cancer patients were included in this study, comprising 18 males (69.2%) and 8 females (30.8%) with a median age of 56 years (Supplementary Table 1). Among these, 24 patients (92.3%) were diagnosed with lung adenocarcinoma (LUAD), one (3.8%) with lung squamous cell carcinoma (LUSC), and one (3.8%) with small cell lung cancer (SCLC). Analysis revealed that IL-6 concentrations were significantly higher in MPE compared with serum from the same patients (Supplementary Fig.
Quasiparticle trapping in quench dynamics of superconductor/quantum dot/ superconductor Josephson junctions
With the aid of Keldysh nonequilibrium Green's functions, we investigate the quench dynamics in a superconductor–quantum dot–superconductor (S-QD-S) Josephson junction during transient transport processes going beyond the wide-band limit. We calculate the transient current when the bias is suddenly turned off/on.
High-Efficiency Photoelectric Detector Based on a $p$-$n$ Homojunction of Monolayer Black Phosphorus
We numerically investigate the high-efficiency photovoltaic effect in a lateral p-n homojunction based on monolayer black phosphorus (MBP) by using the nonequilibrium Green’s function combined with the density-functional theory. Because of the built-in electric field of the p-n junction and the wrinkle structure of MBP, the photocurrent excited by either linearly or elliptically polarized light is significantly enhanced in a wide photon energy range.
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