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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Lipid metabolism at the intersection of rheumatoid arthritis and atherosclerosis
Abstract Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic, symmetric polyarticular synovitis, with a global prevalence of approximately 0.5%-1%. Its pathogenesis involves a complex interplay of genetic and environmental factors, as well as abnormal immune activation. RA patients face a significantly increased risk of cardiovascular disease, with atherosclerosis (AS) and its complications being the leading cause of mortality.
Dysregulated autophagy at the nexus of type 2 diabetes mellitus and pancreatic cancer pathogenesis
1 Background Diabetes mellitus is a global metabolic disorder characterized by chronic hyperglycemia, primarily arising from insulin secretion deficiency due to pancreatic β-cell dysfunction and insulin resistance in peripheral tissues (1). According to the latest data from the International Diabetes Federation (IDF), the global diabetic population exceeds 537 million and is projected to rise to 783 million by 2045, with type 2 diabetes mellitus (T2DM) accounting for over 90% of cases (2).
MicroRNA-221: A Context-Dependent Mediator in Human Diseases-From Molecular Mechanisms to Clinical Translation
Submitted: 30 October 2025 You are already at the latest version MicroRNA-221 (miR-221), a conserved small non-coding RNA, acts as a pivotal modulator of biological processes across multiple organ systems, the dysregulation of which is closely linked to the pathogenesis of various human diseases.
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