Wanying He

Abstract Development of castration resistance and distant metastasis remain two major clinical challenges in prostate cancer (PCa) treatment. By analyzing multiple public cancer datasets, we found that ribosomal protein S15 (RPS15) is overexpressed in PCa and related to its metastasis. Beyond its canonical role as a structural component of the ribosome, emerging evidence has highlighted the extraribosomal functions of RPS15 in disease progression.

Environmental Science & Technology Cite this: Environ. Sci. Technol. 2025, XXXX, XXX Click to copy citationCitation copied! . This publication is licensed under CC-BY-NC-ND 4.0 . You are free to share (copy and redistribute) this article in any medium or format within the parameters below: Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted.

1Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China 2Chronic Airways Diseases Laboratory, Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China 3Department of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China Background: Current clinicopathological risk factors lack the precision necessary for accurate prediction of central...