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Mesenchymal and Pluripotent Stem Cell‐Based Strategies for Cardiac Regeneration: Mechanisms, Challenges, and Future Directions
Conflicts of Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Data Availability Statement Data sharing is not applicable to this article, as no datasets were generated or analyzed during the current study.
Mesenchymal and Pluripotent Stem Cell‐Based Strategies for Cardiac Regeneration: Mechanisms, Challenges, and Future Directions
Conflicts of Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. References 1, , , et al., “Revolutionizing Cardiac Care: A Comprehensive Narrative Review of Cardiac Rehabilitation and the Evolution of Cardiovascular Medicine,” Cureus 15, no. 10 (2023): 46469.
Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination
Highlights • Nuclear import carrier Hikeshi is essential for CNS myelination and remyelination • Loss of Hikeshi inhibits nuclear translocation of HSP70s upon differentiation • HSP70s protect SOX10 from E3 ligase FBXW7-mediated ubiquitination degradation • Hyperthermia can effectively promote myelination and remyelination Summary Dysregulation of factors in nucleocytoplasmic transport is closely linked to neural developmental diseases.
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