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Articles by Wei-Ming Su
Plasma Proteomic Signatures Predict Incident Amyotrophic Lateral Sclerosis: A Prospective Study Stratified by C9orf72 Expansion
1 Background Amyotrophic lateral sclerosis (ALS) is a fatal and heterogeneous neurodegenerative disease of the central nervous system, characterized by challenges in early diagnosis and an unfavourable prognosis, with a median survival of 3–5 years following symptom onset [1].
Systematic druggable genome‐wide Mendelian randomization identifies therapeutic targets for sarcopenia
Introduction Sarcopenia has been recognized as a muscle disease, characterized by age-related loss of muscle mass and function.1 According to the definition of the European Working Group on Sarcopenia in Older People (EWGSOP), 4.6% of men and 7.9% of women with an average age of 67 suffer from sarcopenia.2 It is a major cause of frailty, functional decline, increased risk of falls, and premature death in the elderly, all imposing a heavy burden on the healthcare system.3 Lifestyle measures,...
A New Readahead Framework for SSD-based Caching Storage in IoT Systems
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 23 January 2024 / Approved: 23 January 2024 / Online: 23 January 2024 (13:38:41 CET) Chang, H.; Su, W.; Chang, D. A New Readahead Framework for SSD-based Caching Storage in IoT Systems. Preprints 2024, 2024011695. https://doi.org/10.20944/preprints202401.1695.v1 Chang, H.; Su, W.; Chang, D. A New Readahead Framework for SSD-based Caching Storage in IoT Systems. Preprints 2024, 2024011695.
Systematic druggable genome-wide Mendelian randomisation identifies therapeutic targets for Alzheimer’s disease
Systematic druggable genome-wide Mendelian randomisation identifies therapeutic targets for Alzheimer’s disease Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Systematic druggable genome-wide Mendelian randomisation identifies therapeutic targets for Alzheimer’s disease
Materials and methods The overall study design is illustrated in figure 1. Further details of the methods and materials used are provided as follows.
Genetically Predict Diet‐derived Antioxidants and Risk of Neurodegenerative Diseases Among Individuals of European Descent: A Mendelian Randomization Study
1 Introduction Neurodegenerative diseases (NDDs) are a major health problem for the world's aging population. NDDs are an extensively heterogeneous group of diseases that affect the nervous system and are one of the most common causes of disability worldwide (Heemels 2016). The prevalence of NDDs is rapidly increasing, leading to a substantial rise in associated social and economic burdens (Hou et al. 2019, GBD 2019 Dementia Forecasting Collaborators 2022, Nandi et al. 2022).
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