Wei-Ying Chen

1 Introduction Hepatocellular carcinoma (HCC) is one of the most lethal cancers affecting the digestive tract, ranking among the top five [1]. Additionally, it is the third leading cause of cancer-related deaths worldwide [2]. For patients in the very early or early stages of HCC where surgery is not recommended, local ablation is a common standard treatment [3, 4]. Percutaneous radiofrequency ablation (RFA) is the primary method of local ablation, typically performed percutaneously.

Introduction Multiple endocrine neoplasia type 2 (MEN2) is a rare neuroendocrine tumor syndrome that follows an autosomal dominant inheritance pattern. It is characterized by medullary thyroid carcinoma (MTC), which may or may not be accompanied by pheochromocytoma (PHEO), hyperparathyroidism (HPTH), and extra-endocrine features (1, 2). Clinically, there are two distinct subtypes: MEN2A (OMIM# 171400; approximately 95% of MEN2 cases) and MEN2B (OMIM# 162300; approximately 5%) (1).

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