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Weibang Wu on Muck Rack

Weibang Wu

As seen in: Frontiers in Immunology
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Articles

Integrative single-cell and bulk transcriptomic analysis identify R-loop-associated gene signatures driving immune-inflammatory networks in acute pancreatitis

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By Tianying Zhang, Shujie He, Yueqiu Qin, Lujuan Pan, Weibang Wu, Zujian Zhang, Cailing Zhang, Chaojun Lan
| Frontiers in Immunology
Abstract Background: R-loop dysregulation has been implicated in chronic inflammation via DNA damage and cytoplasmic ssDNA release, yet its role in acute pancreatitis (AP) remains to be systematically investigated. This study aimed to identify R-loop-related biomarkers in AP and elucidate their potential roles in immune-inflammatory networks through integrative bioinformatics analysis and in vitro experimental validation.
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