Weiying Lin
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A TICT mechanism-based viscosity fluorescent probe for monitoring viscosity in inflammatory cells
A TICT mechanism-based viscosity fluorescent probe for monitoring viscosity in inflammatory cells† Viscosity, as a fundamental biophysical parameter of cellular microenvironments, critically regulates physiological processes, including molecular transport and signal transduction. Lysosomes, functioning as pivotal organelles, orchestrate essential biological activities such as macromolecular degradation and autophagic flux.
Development of cysteine-sensitive bimodal probes for in situ monitoring of early-stage pulmonary fibrosis progression and therapeutic effects
Development of cysteine-sensitive bimodal probes for in situ monitoring of early-stage pulmonary fibrosis progression and therapeutic effects† Pulmonary fibrosis (PF) is a chronic interstitial lung disease characterized by excessive extracellular matrix deposition and lung scarring, leading to impaired lung function, severe respiratory distress, and potentially fatal outcomes. Early diagnosis of PF is crucial for optimizing treatment strategies to improve patient prognosis.
A lipid droplet-specific fluorescent probe for acute liver injury and tumor diagnosis via aberrant polarity changes
A lipid droplet-specific fluorescent probe for acute liver injury and tumor diagnosis via aberrant polarity changes† A biological microenvironment is characterized by its complexity and variability, with alterations in lipid droplet (LDs) polarity being strongly linked to multiple pathological conditions such as acute liver injury. Thus, assessing the polarity of LDs holds particular significance in diagnosing conditions related to LD polarity.
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