Wenying Qiu

Abstract Microplastics and nanoplastics (MNPs) are emerging global contaminants of concern, owing to their ability to penetrate human tissues, although their health risks are unknown. MNPs have been detected in several organs, including the brain, but their concentrations in, and effects on, this organ remain largely unexplored.

Abstract Abnormal aggregation of amyloid-β protein (1–42) (Aβ42) is the primary pathology in Alzheimer’s disease (AD). Two types of Aβ42 fibrils have been identified in the insoluble fraction of diseased human brains. Here, we report that the fraction previously deemed ‘soluble’ during sarkosyl extraction of AD brains actually harbors numerous amyloid fibrils, with a looser bundling than those in the insoluble fraction.

Research Article Tao Jiang, Tao Jiang Sensors and Microsystems Laboratory, Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, 518055 China Department of Mechanical Engineering, Berkeley Sensors and Actuators Centre, University of California Berkeley, Berkeley, CA, 94720 USA Search for more papers by this author Wenying Qiu, Wenying Qiu Sensors and Microsystems Laboratory, Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, 518055 China Department of...