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Wisna Novera on Muck Rack

Wisna Novera

As seen in: Mary Ann Liebert, Inc.
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Cysteine Deprivation Targets Ovarian Clear Cell Carcinoma Via Oxidative Stress and Iron−Sulfur Cluster Biogenesis Deficit

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By Dawn Sijin Nin, Wisna Novera, Zheng-Wei Lee, Melvin Zi-Yu Dai
| Mary Ann Liebert, Inc.
Introduction Epithelial ovarian cancer is classified into four major types based on histopathology: (i) serous, (ii) clear cell, (iii) endometrioid, and (iv) mucinous. Of the four histotypes, ovarian clear cell carcinoma (OCCC) is known to be more resistant to conventional platinum-based therapy (5, 7, 20). For recurrent and chemoresistant OCCC, treatment options remain limited to coupling cytotoxic drugs such as docetaxel, paclitaxel, and irinotecan with platinum-based therapy.
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