Wouter-Jan Rappel

Keywords collective migration rotational migration invasive migration adhesion matrix remodeling matrix metalloproteinase adherens junctions MT1-MMP ITGβ1 Introduction Exocrine organs, such as the mammary, salivary, and digestive glands, are composed of suprastructural networks of terminal acini connected to secretory ducts.

Abstract When cells of the social amoeba Dictyostelium discoideum are starved of nutrients they start to synthesize and secrete the chemical messenger and chemoattractant cyclic Adenosine Mono Phosphate (cAMP). This signal is relayed by other cells, resulting in the establishment of periodic waves. The cells aggregate through chemotaxis towards the center of these waves.

Abstract Diverse interactions among species within bacterial colonies lead to intricate spatiotemporal dynamics, which can affect their growth and survival. Here, we describe the emergence of complex structures in a colony grown from mixtures of motile and non-motile bacterial species on a soft agar surface. Time-lapse imaging shows that non-motile bacteria 'hitchhike' on the motile bacteria as the latter migrate outward.