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Xiao-Han Ying on Muck Rack

Xiao-Han Ying

As seen in: The Journal of Clinical Investigation
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Articles

Comprehensive genomic profiling of triple-negative breast cancer metastases identifies role of PKD1 in immunotherapy resistance

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By Xiu-Zhi Zhu, Yi-Fan Zhou, Xiao-Han Ying
| The Journal of Clinical Investigation
Abstract The multi-omics data represented by genomic data from patients with metastatic triple-negative breast cancer (TNBC) is crucial for precision treatment, yet data on genomic alterations in metastatic cohorts and Chinese populations remains limited. We performed targeted sequencing of 296 metastatic TNBC samples from 296 patients treated at Fudan University Shanghai Cancer Center (October 2018 to November 2020) using a 484-gene panel, identifying 796 metastatic events across 18 organ sites.
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