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Xiao-Ying Yao on Muck Rack

Xiao-Ying Yao

As seen in: Nature, Multiple Sclerosis and Related Disorders
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Articles

Human umbilical cord mesenchymal stromal cells therapy for neuromyelitis optica spectrum disorder: a phase 1/2a trial

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By Xiao-Ying Yao, Zhong-jiao Lu, Nan Zhao, Li Xie, Yi-Shu Wang, Ying Zhang, Yan Lin, Ye Deng, Xi-Ying Wang, Yi Chen, He Zhu, Lin-Feng Li, Hui-Ming Xu, Jie Ding, Yi-Fan Wu, Ze Wang, Ya-Ying Song, Kan Wang, Yan Zhou, Quan Guo, Bi-yun Qian, Yang-Tai Guan, Chun-Ran Xue, Xu-Zhong Pei, Meng-Ze Zhang, Wen-Bin Wan, Hui-Ying Qiu, Yu-Yan Jin, Li-Ping Ni, Jia-Li Yan, Jia-Hui Xue, Yu-Fang Mei, Hao-Jun Yu
| Nature Verified
Abstract Current treatments for neuromyelitis optica spectrum disorder (NMOSD) highlight recurrence management, while little attention is paid to the relief of residual neurological dysfunction. Here we aimed to evaluate the safety and efficacy of human umbilical cord-derived mesenchymal stromal cells (hUC-MSCs) in reducing relapses and mitigating neurological impairments.
Open in Who Shared Issue with article?

Serum albumin level is associated with the severity of neurological dysfunction of NMOSD patients

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By Yi-Fan Wu, Xiao-Ying Yao, Mei-Chun Gao, Rong-Hua Hong
| Multiple Sclerosis and Related Disorders Verified
Highlights • Serum albumin (SA) negatively correlated with EDSS in acute phase of NMOSD. • A low SA level was an independent factor of severe disability in acute attacks. • Serum albumin negatively associated with IL-33 in acute phase of NMOSD. • SA may play a protective role in NMOSD partly through its interaction with IL-33. Abstract Background Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory autoimmune disease of the central nervous system.
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