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Articles by Xiaofei He
ZmSGT1-mediated competitive protection of ZmBBI1 enhances maize resistance to Rhizoctonia solani
INTRODUCTION Maize (Zea mays L.) ranks among the world's most economically significant cereal crops, providing a foundational source of human nutrition, livestock feed, and industrial feedstocks. Banded leaf and sheath blight (BLSB), incited by the necrotrophic basidiomycete Rhizoctonia solani Kühn, represents a devastating soil-borne disease that threatens global maize productivity on a massive scale (Hooda et al., 2017; Kumar et al., 2021; Hamidi et al., 2023).
High-accuracy hyperspectro-polarimetric real-time imaging via a deep learning empowered infrared meta-sensor
Abstract Light inherently carries multidimensional information, including intensity, polarization, and spectrum. Employing a miniaturized device to simultaneously, instantaneously, and accurately capture the multidimensional information of incident light in a single exposure holds significant applications across numerous fields, but remains challenging.
Biomonitoring of per- and polyfluoroalkyl substances (PFAS) in sportfish consumers in the Great Lakes – Milwaukee, Wisconsin
Abstract The Milwaukee Angler Study was initiated in 2017 as part of the Biomonitoring of Great Lakes Populations Program (BGLP-III) to examine two adult populations at high risk of per- and polyfluoroalkyl substances (PFAS) exposure from consumption of PFAS-contaminated sportfish: licensed anglers near the Milwaukee Estuary Area of Concern (AOC) and Burmese refugees for whom fish is a dietary staple.
Impact of Heat Transfer Modes on Drying Kinetics, Thermodynamics, and Quality Attributes of Kelp ( Saccharina japonica )
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions. References , , and . 2020. “Influence of Drying Methods on the Thermodynamic Parameters, Effective Moisture Diffusion and Drying Rate of Wastewater Sewage Sludge.” Renewable Energy 147, no. 1: 1107–1119. , , , et al. 2013.
Advances in deciphering the mechanisms of salt tolerance in Maize
ABSTRACT Maize (Zea mays L.) is a vital crop worldwide, serving as a cornerstone for food security, livestock feed, and biofuel production. However, its cultivation is increasingly jeopardized by environmental challenges, notably soil salinization, which severely constrains growth, yield, and quality.
Cloning and sequence analysis of goat GSK3B gene and its effect on lipogenesis in goat intramuscular adipocytes
ABSTRACT The aim of this study was to detect the expression of GSK3B gene in different tissues of goats and the expression level of intramuscular precursor adipocytes at different differentiation periods, and to further reveal the effects of overexpression and interferences of GSK3B gene on lipid deposition in intramuscular precursor adipocytes of goats.
CircFndc3b Mediates Exercise‐Induced Neuroprotection by Mitigating Microglial/Macrophage Pyroptosis via the ENO1/KLF2 Axis in Stroke Mice
1 Introduction Ischemic stroke, accounting for ≈80% of all stroke cases, presents a critical public health concern due to its high rates of morbidity, mortality, and disability.[1] The underlying pathophysiology of ischemic stroke is multifaceted, often leading to ischemia-reperfusion injury, predominantly driven by neuroinflammation.[2, 3] As neuroinflammation significantly exacerbates ischemic brain damage, mitigating this process is essential for promoting neurological recovery following...
Blood Brain Barrier‐Crossing Delivery of Felodipine Nanodrug Ameliorates Anxiety‐Like Behavior and Cognitive Impairment in Alzheimer's Disease
1 Introduction Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder leading to cognitive impairment and dementia, it poses a significant global health challenge, which is getting worse due to aging populations.[1] Although the pathogenesis of AD has kept unclear, recent advancements in understanding AD pathophysiology have highlighted the critical role of neuroinflammation, mitochondrial dysfunction, and protein aggregation, particularly amyloid-beta (Aβ) and...
The role of bile acid receptor TGR5 in regulating inflammatory signalling
1 INTRODUCTION Takeda G protein-coupled receptor 5 (TGR5), also named as G protein-coupled bile acid receptor 1 (GPBAR1) or G protein-coupled receptor 19 (GPCR19 or GPR131), is a membrane receptor (M-BAR) of bile acids (BAs).1 Its gene has one exon that encodes seven transmembrane domains, which consist of 330 amino acids.2, 3 TGR5 belongs to the largest cell membrane receptor GPCR family,4 and approximately 30%–50% of all pharmaceuticals on the market today exert their therapeutic effects by...
Modeling Noncommutative Composition of Relations for Knowledge Graph Embedding
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Chao Xiang 1,*, Cong Fu 1, Deng Cai 1 and Xiaofei He 1,2 1 State Key Lab of CAD&CG, Zhejiang University, Hangzhou 310058, China 2 Fabu Inc., Hangzhou 310030, China * Author to whom correspondence should be addressed.
A novel reverse transcription-multiple inner primer loop-mediated isothermal amplification (RT-MIPLAMP) for visual and sensitive detection of SARS-CoV-2
A novel reverse transcription-multiple inner primer loop-mediated isothermal amplification (RT-MIPLAMP) for visual and sensitive detection of SARS-CoV-2 Xiaofei He, Fengxia Su, Yutong Chen and Zhengping Li Abstract Since the end of 2019, outbreaks of COVID-19 pandemics have continued in different areas worldwide, which exacerbates the need for rapid, sensitive and simple methods for diagnosis.
Specific detection of fusion transcripts based on duplex-specific nuclease and isothermal exponential amplification reaction
Specific detection of fusion transcripts based on duplex-specific nuclease and isothermal exponential amplification reaction Fengxia Su, Tian Li, Xiaofei He and Zhengping Li Abstract The fusion genes are mostly found in tumor tissues, but is in low expression level in healthy tissues, making them good candidate biomarkers for tumor diagnosis and therapy.
Sensitive detection of fusion transcripts with padlock probe-based continuous cascade amplification (P-CCA)
Sensitive detection of fusion transcripts with padlock probe-based continuous cascade amplification (P-CCA) Gene fusion, resulted from chromosomal rearrangements, is the juxtaposition of two or more original genes into the same set to form a functional gene. The significant specificity of fusion genes for tumor cells makes them promising candidates of diagnostic biomarkers and therapeutic targets.
Block-Level Link Analysis
Link Analysis has shown great potential in improving the performance of web search. PageRank and HITS are two of the most popular algorithms. Most of the existing link analysis algorithms treat a web page as a single node in the web graph. However, in most cases, a web page contains multiple semantics and hence the web page might not be considered as the atomic node. In this paper, the web page is partitioned into blocks using the visionbased page segmentation algorithm.
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