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Articles by Xiaohui Su
AG490 attenuates neuroinflammation in experimental autoimmune encephalomyelitis possible through promoting autophagy
Abstract Multiple sclerosis (MS) is an autoimmune inflammatory disorder that affects the central nervous system (CNS) and has been extensively studied in experimental autoimmune encephalomyelitis (EAE) animal models. AG490, which has potent neuroprotective activity, is used to investigate immune disorders associated with the CNS.
mtROS-NF-κB signaling supports ILC3 function and survival during sepsis-induced intestinal injury
Abstract Sepsis frequently induces intestinal barrier injury, which exacerbates systemic inflammation, and contributes to high mortality. Group 3 innate lymphoid cells (ILC3s) are key regulators of mucosal immunity, yet their role in sepsis-associated intestinal injury remains incompletely understood. We found circulating ILCPs were reduced in patients with sepsis.
Distinction Between Benign and Borderline/Malignant Phyllodes Tumor in Breast Mammography and Ultrasound Based on Radiomics Methods
Abbreviations MG (mammography) US (ultrasound) PTs (phyllodes tumors) LASSO (least absolute shrinkage and selection operator) ML (machine learning) ROC (receiver operating characteristic curve) AUC (area under the curve) CI (confidence interval) ACC (accuracy) NPV (negative predictive value) PPV (positive predictive value) Sens (sensitivity) Spec (specificity) LR (logistic regression) SVM (support vector machine) RF (random forest) ExtraTrees (extremely randomized trees) XGBoost (extreme...
Frontiers | A radiomic model leveraging conventional and Hessian matrix-based radiomic features from DCE-MRI for predicting efficacy of neoadjuvant chemotherapy in patients with HER2-low breast cancer
Introduction Breast cancer is one of the most prevalent malignancies worldwide, posing significant challenges in both diagnosis and therapy. In 2022 alone, there were 2.3 million new breast cancer diagnoses worldwide, resulting in approximately 665 thousand deaths (1). The Human Epidermal Growth Factor Receptor 2 (HER2) gene is a crucial biomarker in breast cancer, impacting classification, treatment decisions, and disease prognosis (2).
Mesothelin as a biomarker and potential therapeutic target in rheumatoid arthritis bone destruction
Keywords rheumatoid arthritis bone destruction osteoclast MSLN PI3K/AKT pathway Introduction Rheumatoid arthritis (RA) is a prevalent autoimmune disease with global impact, particularly on the adult workforce. The primary pathological characteristic of RA is the destruction of joint bones, one of the major causes of disability in affected individuals.
A Boosting Strategy of Photovoltaics by Stacking Monolayer InSe and β‐Sb into Heterostructure
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MDFA-Net: Multi-Scale Differential Feature Self-Attention Network for Building Change Detection in Remote Sensing Images
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Identification of Rare Wildlife in the Field Environment Based on the Improved YOLOv5 Model
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
A Fast Detection Algorithm for Change Detection in National Forestland “One Map” Based on NLNE Quad-Tree
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Sialidosis type 1 without cherry-red spots: a case report and literature review
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Development of MRI-Based Deep Learning Signature for Prediction of Axillary Response After NAC in Breast Cancer
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Combining the Back Propagation Neural Network and Particle Swarm Optimization Algorithm for Lithological Mapping in North China
3. Results 3.1. Lithological Map of Diorite With the improved PSO algorithm, we obtained the optimal model of the lithological map. The number of network nodes in the input, hidden, and output layers is 15, 12, and 2, respectively. The learning rate is 0.3. The impulse coefficient is 0.45. The error threshold is 0.005. We obtained the optimal model by comprehensively considering the accuracy and kappa of the models. The accuracy of the optimal model is 92.11% and the kappa is 0.81.
SPARC: a potential target for functional nanomaterials and drugs
Introduction Targeted therapy of inflammation and tumor is the main focus of the current research. To date, there is no perfect treatment plan for rheumatoid arthritis, which is a well-known immunodeficiency inflammatory disease (Watanabe et al., 2022). With the development and synthesis of functional nanomaterials, serum albumin, such as human serum albumin (HSA), has become a popular material used in the cure of rheumatoid arthritis.
Evaluation of Lymphatic Vessel Invasion Determined by D2-40 Using Preoperative MRI-Based Radiomics for Invasive Breast Cancer
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Numerical Study on the Unstable Flow Dynamics of Wormlike Micellar Solutions Past a Sphere in the Creeping Flow Regime
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Xiaohui Su 1,*, Zhiguo Wang 1, Jialun Liu 1 and Song Wu 2 1 School of New Energy, Xi’an Shiyou University, Xi’an 710065, China 2 School of Mechanical Engineering, Xi’an Shiyou University, Xi’an 710065, China * Author to whom correspondence should be addressed.
Bioengineering | Free Full-Text | CFD Computation of Flow Fractional Reserve (FFR) in Coronary Artery Trees Using a Novel Physiologically Based Algorithm (PBA) Under 3D Steady and Pulsatile Flow Conditions
3. Results and Discussion The mesh generation for the blood vessels was performed using the open-source cfMesh utility, which is part of OpenFOAM and generates volumetric meshes of unstructured Cartesian types. cfMesh is also able to automatically generate tetrahedral meshes for a variety of geometries, as shown in . A mesh sensitivity analysis was conducted [], and the same models were used in this study.
Maintenance of Primary Hepatocyte Functions In Vitro by Inhibiting Mechanical Tension-Induced YAP Activation
Highlights • Mechanical tension-induced Yap activation triggers hepatocyte dedifferentiation • Confinement of cell spreading is sufficient to inhibit hepatocyte dedifferentiation • A chemical cocktail, LBDXL, maintains hepatocyte functions by targeting stress fibers • LBDXL hepatocytes resemble primary hepatocytes in gene expression and functions Summary Hepatocytes are the primary functional cells of the liver, performing its metabolic, detoxification, and endocrine functions.
Surface state controlled ultrahigh selectivity and sensitivity for UV photodetector based on individual SnO2 nanowires
For nanostructures with large surface-to-volume ratio, quantities of dangling bonds can create affluent surface states due to the breaking of lattice periodicity on their surfaces. Herein, surface states are utilized for the development of high-performance photodetectors based on individual SnO2 nanowires.
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