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Articles by Xiaolan Sun
Ultrasound-responsive erythrocyte-fused vesicles for targeted theranostics of Wilms’ tumor
Abstract Wilms’ tumor (WT) is the most common renal tumor of childhood. Despite clinical chemotherapy and radiotherapy showed favorable treatment-response, serious side effects caused by the absence of efficient targeted therapeutic fumulations remain a major challenge in clinical practice. Here, we identified neural cell adhesion molecule 1 (NCAM1) as a potential delivery target by bioinformatic analysis and selected an NCAM1-targeting peptide (NTP) as its specific ligand.
Copper ions (${{\rm Cu}^{2 +}}$) play critical roles in biological systems but induce toxicity at elevated concentrations. This study, to our knowledge, reports a novel ratio-metric fluorescence sensor based on near-infrared (NIR)-emissive PbS quantum dot (QD)-doped hydrogel fiber sensor for real-time, selective detection of ${{\rm Cu}^{2 +}}$. The sensor employs a biocompatible and mechanically flexible HF with a core-cladding structure to confine light within the core for efficient transmission.
Ultrasound Measurements of Skeletal Muscle Predict Chemotherapy Toxicity in Non-Small Cell Lung Cancer
Abstract Background Non-small cell lung cancer (NSCLC) patients often experience skeletal muscle mass (SMM) reduction, increasing chemotherapy toxicity risk. Although CT and MRI scans are commonly used to assess SMM, their limitations exist. Ultrasound, a convenient alternative, may serve as a predictive tool for chemotherapy toxicity. Methods This multi-center, prospective study analyzed 163 NSCLC patients undergoing platinum-based chemotherapy.
Identification of Compound Heterozygous Variants in OBSCN Gene Associated With Rhabdomyolysis: A Case Report
1 Introduction OBSCN, located on chromosome 1q42, is a protein-coding gene that contains over 80 exons and encodes nearly 8000 amino acids (obscurins). Obscurin is a component of the sarcomere that binds near the M-line or the Z-disc. Previous studies showed that it could interact with titin, myosin, and small ankyrin1. It is thought to be a structural protein that links the M-line of the sarcomere to the sarcoplasmic reticulum (Fukuzawa et al. 2008; Kontrogianni-Konstantopoulos et al.
Ancient Genome of Broomcorn Millet from Northwest China in Seventh Century CE: Shedding New Light to Its Origin and Dispersal Patterns
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COVID-19 re-positive cases in elderly malnourished patients
Back to Journals » Clinical Interventions in Aging » Volume 19 Authors Chen J, Luo D, Sun C, Sun X, Dai C, Hu X, Wu L, Lei H, Ding F, Chen W, Li X Received 11 November 2023 Accepted for publication 27 February 2024 Published 9 March 2024 Volume 2024:19 Pages 421—437 DOI https://doi.org/10.2147/CIA.S449338 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Maddalena Illario Jiao Chen, Danmei Luo, Chengxia Sun, Xiaolan...
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