Xiaolei Yin
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Bladder metastasis from gastric cancer presenting as acute post-renal obstruction during immunotherapy: a case report
Abstract Bladder metastasis from gastric cancer is extremely rare and may be misdiagnosed, particularly during immunotherapy, when new urinary symptoms can be attributed to genitourinary immune-related adverse events. We report a case of a 35-year-old man with advanced gastric cancer who initially responded to chemotherapy combined with sintilimab, an anti–Programmed Death-1 (PD-1) inhibitor.
Full article: Integrated Analysis of Ferroptosis- and Cellular Senescence-Related Biomarkers in Atherosclerosis Based on Machine Learning and Single-Cell Sequencing Data
Abstract Background Atherosclerosis is a chronic inflammatory disease characterized by lipid accumulation in the vascular wall. The roles of ferroptosis and cellular senescence in Atherosclerosis remain unclear. This study aimed to identify genes related to ferroptosis and cellular senescence in Atherosclerosis using bioinformatics approaches. Methods Atherosclerosis gene expression datasets were obtained from the GEO database.
Molecular typing and mutational characterization of rectal neuroendocrine neoplasms
1 INTRODUCTION Neuroendocrine neoplasms (NENs), which have seen a rapid increase in incidence in recent years, can occur in whole-body organs and tissues. According to the 2019 World Health Organization (WHO) classification of endocrine and neuroendocrine tumors (NETs), NENs are classified as well-differentiated NETs, poorly differentiated neuroendocrine carcinomas (NECs) and mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs).
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