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Xiner Ying

As seen in: Nature
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Articles

m 6 A modification by METTL3 enhances BIRC6 translation to promote liver tumorigenesis

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By Chenliang Wang, Lang Song, Shixun Han, Jie J. Cao, Zezhen Lu, Mei Tang, Qi Zhou, Xiaolei Cao, Bing Wu, Yuchao Cao, Xiner Ying, Yijie Guo, Xueli Bai, Tingbo Liang, Jun Qin, Xin-Hua Feng, Jianzhao Liu, Bin Zhao, Nairen Zheng
| Nature Verified
Abstract N6-methyladenosine (m6A) is the most prevalent internal modification of mRNA and is frequently dysregulated in cancer. However, the roles of m6A and its modifiers, such as the methyltransferase METTL3, remain controversial in primary tumors. We report that METTL3 is upregulated in the highly proliferative human S2 and mouse M2 subtypes of hepatocellular carcinoma (HCC).
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Nuclear-m 6 A-Label-Seq Enables Transcriptome-Wide Nuclear m 6 A Profiling at Single-Base Resolution Click to copy article link Article link copied!

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By Chenyang Huang, Xiner Ying, Xiao Shu
| dx.doi.org
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An RNA Methylation-Sensitive AIEgen-Aptamer Reporting System for Quantitatively Evaluating m6A Methylase and Demethylase Activities

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By Xiner Ying, Chenyang Huang, Tengwei Li, Ting Li
| dx.doi.org
Download Hi-Res ImageDownload to MS-PowerPointCite This:ACS Chem. Biol. 2023, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
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