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Xingyin Zhang on Muck Rack

Xingyin Zhang

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Articles

Genome-resolved and culture-based atlas of the feline gut microbiome enables host-adapted probiotic development

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By Feilong Deng, Ying Fan, Jinxia Yan, Yan Guo, Minghui Li, Yunjuan Peng, Lingling Zhao, Feitong Liu, Yanyi Zheng, Baichuan Deng, Jinping Deng, Hui Jiang, Jianmin Chai, Jiangchao Zhao, Ying Li, Xingyin Zhang, Shengfeng Chen
| Nature Verified
Abstract Domestic cats (Felis catus) depend on their gut microbiome for metabolism, immunity, and pathogen defense, yet its genomic characterization remains limited. We combined large-scale metagenomics and culturomics to define the feline gut microbiome and identify indigenous probiotic candidates. Analysis of 412 feline fecal metagenomes produced 2852 strain-resolved metagenome-assembled genomes (MAGs) grouped into 514 species-level genome bins, including 106 putative novel taxa.
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