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Xinying Zhang on Muck Rack

Xinying Zhang

As seen in: Color Research & Application, Nature, Wiley Online Library, Frontiers, MDPI, ACS Publications, Science Magazine, Royal Society of Chemistry, Cell Press, Canadian Journal of Infectious Diseases & Medical Microbiology and
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Articles

A core transcriptional regulatory circuitry controls super-enhancer-driven activation of LGR5 in colorectal cancer

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By Min Ye, Shilan Wang, Yongheng Chen, Hongchao Ma, Ying Ying, Wenlong Ma, Canjie Ma, Xianming Liu, Weitao Wu, Bushra Fordil, Min Jia, Ru Geng, Xinying Zhang, Xiaoman Song, Tianle Lin, Maolin Wang, Wei-Guo Zhu, Xing-Sheng Shu
| Nature Verified
Abstract The core transcriptional regulatory program governed by a small set of master transcription factors is pivotal for establishing context-specific cellular features. Here, we report the roles of master factor MYC in actively regulating cancer-type specific super-enhancer activity and orchestrating a super-enhancer-dependent core transcriptional regulatory circuitry consisting of MYC, ETS2, and FOXP1 in colorectal cancer.
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Effects of meropenem plus ulinastatin on inflammatory response and complications in patients with severe septic shock

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By Dan Wu, Wei Ni, Xinying Zhang, Xiaodong Liu
| Frontiers
Abstract Aim: To evaluate whether receipt of ulinastatin in addition to meropenem-based standard care was associated with inflammatory, coagulation, perfusion, and clinical outcomes in patients with severe septic shock. Methods: This single-center retrospective, non-randomized comparative cohort study included 106 consecutive patients with severe septic shock treated between January 2023 and November 2025.
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Determination of the median effective dose (ED₅₀) of oliceridine combined with propofol for inhibiting gastroscope insertion responses in adult patients undergoing painless gastroscopy

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By Xiaojing Zhang, Weimin Qin, Xinying Zhang, Wenbo Liang, Zhiqiang Ren, Qing Ma, Li Zhou Verified, Longbin Zheng
| Frontiers
Abstract Background: Propofol is the most frequently administered intravenous anesthetic in painless gastroscopy. Oliceridine, a novel μ-opioid receptor agonist, exhibits analgesic effects while reducing adverse reactions. The combination of propofol and oliceridine has shown promising efficacy in clinical practice. However, the exploration of the specific effective dosage of oliceridine in painless gastroscopy is still in its early stages.
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