Xue Ying
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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Advanced nanoformulations of NUAK1 regulate NLRP3 inflammasome for preeclampsia management in mice
Abstract Preeclampsia (PE) is a severe pregnancy complication driven by placental dysfunction and oxidative stress, which currently lacks effective targeted therapies. Here, we evaluated the therapeutic potential of folic acid-modified lipid nanoparticles (NPs) co-loaded with polydopamine and NUAK Family Kinase 1 (NUAK1), termed FLN@(PDA + NUAK1) NPs, for mitigating PE.
Zoledronic acid enhances the antitumor efficacy of the PSMA CAR-T cells for bone tumors, but impedes the ability to control metastases of prostate cancer in mice
Abstract The chimeric antigen receptor (CAR)-T cell therapy has shown promise for the treatment of hematological and solid tumors. Although CAR-T cells targeting PSMA showed robust antitumor efficacy for prostate cancer in preclinical studies, the clinical benefits of PSMA CAR-T cells are unsatisfactory.
Efficacy and safety of transcutaneous electrical acupoint stimulation to assist bowel cleansing: study protocol for a single-center, single-blind, randomized controlled trial
Abstract Introduction: High-quality bowel preparation is a crucial prerequisite for ensuring the effectiveness of colonoscopy. Although polyethylene glycol (PEG) remains the first-line cleansing regimen recommended by clinical guidelines, its practical application still faces challenges in achieving adequate bowel preparation rates. Transcutaneous electrical acupoint stimulation (TEAS) shows promise in enhancing intestinal motility through gut-brain-microbiota modulation.
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