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Xuejing Lin

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Articles

SCAMP3: a two-front driver of hepatocellular carcinoma via YAP activation and extracellular vesicle export

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By Xiangdong Wang, Jie Shi, Haihua Qian, Liang Wang, Qianni Zong, Hongwei Lv, Guishuai Lv, Bin Sun, Yinghan Su, Longyi Zheng, Chunying Liu, Xuejing Lin
| Nature Verified
Abstract Single-cell transcriptomic analysis of primary hepatocellular carcinoma (HCC) revealed that SCAMP3 is predominantly expressed in metabolically aberrant malignant hepatocyte clusters. Despite its known roles in vesicle transport and extracellular microenvironment regulation, the comprehensive function of SCAMP3 in HCC progression has been largely overlooked.
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