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Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury
1 Introduction Ischemic heart disease is a leading cause of disability and mortality worldwide.[1, 2] Following an attack of myocardial infarction, timely reperfusion has emerged as the most effective treatment strategy, substantially reducing mortality associated with ischemic heart disease.[3, 4] However, the occurrence of myocardial ischemia-reperfusion (IR) injury may offset the beneficial effects of reperfusion therapy,[5] and exacerbate ischemic damage, thereby increasing the risk of...
Characteristics of soil microplastics and ecological risks in the Qilian Mountains region, Northeast Tibetan Plateau
Plastics are widely used because of their versatility, stability, durability, and low cost (Kawecki et al., 2018). However, due to the stability and durability of their chemical structure, plastics are difficult to degrade under natural conditions, and can be accumulated in the environment (Han et al., 2024; Xu et al., 2019).
Intrathecal lentivirus-mediated RNA interference targeting nerve growth factor attenuates myocardial ischaemia-reperfusion injury in rat
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Fig 1 Up-regulation of NGF in thoracic DRG and spinal cord after myocardial ischaemia–reperfusion. (a) Representative photographs of heart sections from Sham and ischaemia–reperfusion group. Myocardial infarct size is expressed as a ratio of IS/AAR.
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