Yaliang Li on Muck Rack

Yaliang Li

As seen in: Nature
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Articles

Clinical application of base editing for treating β-thalassaemia

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By Yongrong Lai, Rongrong Liu, Lijie Wang, Xu-Kai Ma, Yaliang Li, Gaohui Yang, Lingling Shi, Yi-Lin Guo, Zhenbin Wei, Xuemei Zhou, Wenchao Xu, Yaofeng Hou, Annarita Miccio, Bei Yang, Xiaodun Mou, Jia Chen
| Nature Verified
Abstract β-Thalassaemia is caused by reduced or absent production of β-haemoglobin1,2,3,4. Previously, we performed laboratory-scale electroporation of CD34+ haematopoietic stem and progenitor cells from patients with β-thalassaemia using a transformer base editor5,6. The aim was to target the binding motif of the transcription repressor BCL11A in the HBG1 and HBG2 promoters7 to reactivate fetal haemoglobin (HbF) production.
Open in Who Shared Issue with article?

IntentRL: Training Proactive User-intent Agents for Open-ended Deep Research via Reinforcement Learning

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By Zexi Li, Yuexiang Xie, Wenhao Zhang, Yaliang Li
| arxiv.org
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
Open in Who Shared View Duplicates (631) Issue with article?

[2601.04571] Enhancing Multimodal Retrieval via Complementary Information Extraction and Alignment

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By Yuexiang Xie, Yaliang Li, Ying Shen
| arxiv.org
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
Open in Who Shared View Duplicates (452) Issue with article?
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