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Articles by Yang Gu
From formation history to intra-articular service: coupling network evolution, fatigue, degradation, and drug release in adaptive hydrogel microspheres
Abstract Hydrogel microspheres intended for intra-articular delivery are commonly compared by particle size, encapsulation efficiency, equilibrium modulus, static degradation, and cumulative drug release. These endpoints do not recover the specimen’s life-cycle history. Crosslinker transport, reaction kinetics, washing, storage, reconstitution, and needle passage can leave gradients in crosslink density, water content, residual functionality, cargo distribution, and relaxation.
Lake eutrophication increases unprotected organic carbon pools in sediments
Abstract Reactive iron oxide-bound organic carbon (Fe–OC) is a key pathway for long-term carbon burial, but its effectiveness under increasingly widespread eutrophication remains uncertain. Here we show that Fe–OC accounts for 16% of total organic carbon and buries at ~14 Mt C yr−1 in lakes globally, equivalent to ~27% of the marine Fe–OC sink despite lakes covering only ~1.25% of marine area.
Patient-aware single-cell analysis of fibrovascular remodeling in a predominantly colorectal cancer immunotherapy cohort
Abstract Background: Cancer-associated fibroblasts (CAFs) and vascular mural cells may shape extracellular matrix organization in colorectal cancer. However, single-cell comparisons are susceptible to unequal cell recovery, ambient RNA, doublets, treatment-stage mixing, and repeated sampling within patients. We investigated fibrovascular remodeling using patients as the inferential unit and distinguished reproducible signals from donor-concentrated and context-dependent findings.
Reconciling the O3-P3 phase transition in layered oxides to reduce particle strain for stable sodium battery cycling
Abstract O3-type layered positive electrode materials for sodium-ion batteries exhibit high specific energy but suffer from phase transitions during charge-discharge cycling, which generate significant lattice strain and compromise structural integrity.
Computer Science > Computer Vision and Pattern Recognition
Recovering clean 3D scenes from hazy multi-view images is challenging because haze attenuates scene radiance and introduces atmospheric scattering. Recent scattering-aware Gaussian Splatting methods introduce physical haze models into reconstruction, but they often apply degradation in image space or bind medium-related variables to Gaussian primitives, which can entangle clean scene radiance with atmospheric effects.
Silver-Alloy Nanotube-Enhanced Metabolic Fingerprints for the Multimodal Diagnosis of Heart Failure
Yanling Liu and Yang Gu contributed equally to this work. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
Controlled flight of high-thrust ultralight ion-propelled microrobot with integrated sensing
Abstract Ion wind technology holds potential for the miniaturization of flying microrobots, generating thrust without mechanical moving parts, enabling simplified and light designs free from high-frequency actuators. Nevertheless, two fundamental challenges have limited its practical implementation: insufficient payload capacity and inadequate controllability, particularly in multi-degrees-of-freedom flight.
From Resource Repository to Experience Hub: A paradigm shift in academic library orientation programs
This study systematically investigates orientation activities in Chinese academic libraries through comprehensive content analysis. The findings reveal that library orientation has become universally institutionalized across Chinese first-class universities, characterized by high activity intensity, strategic diversification, and hybrid delivery modalities combining in-person and digital formats.
From Setback to Success: A Case Report of Secondary Surgical Strategies for Liposclerosing Myxofibrous Tumor-Related Fractures
1 Introduction Liposclerosing myxofibrous tumor (LSMFT), first described by Ragsdale and Sweet in 1986 [1], is a rare benign bone tumor characterized by a heterogeneous histological composition of mature adipose tissue, fibrous stroma, myxoid matrix, and scattered calcifications [2, 3]. The tumor typically affects the metaphyses of long bones, with the distal femur and proximal tibia being the most common sites [4, 5].
Evaluation of Diagnostic Accuracy of Combined Ultrasound Elastography and Magnetic Resonance Imaging in Breast Cancer
Back to Journals » Breast Cancer: Targets and Therapy » Volume 18 Authors Zhang P , Gu Y Received 29 June 2026 Accepted for publication 27 August 2026 Published 10 September 2026 Volume 2026:18 635995 DOI https://doi.org/10.2147/BCTT.S635995 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Pranela Rameshwar Penghua Zhang,1 Yang Gu2 1Ultrasonic Diagnosis Center, Northwest Women’s and Children’s Hospital,...
Circulating tumor DNA for minimal residual disease and recurrence surveillance in hepatocellular carcinoma: current evidence and a translational roadmap
Abstract Recurrence remains a major cause of failure after curative-intent therapy for hepatocellular carcinoma (HCC), including resection, ablation, and liver transplantation. Current surveillance relies on imaging and serum biomarkers, but radiologic relapse may lag behind biological recurrence. This gap has focused attention on circulating tumor DNA (ctDNA) and related cell-free DNA (cfDNA) approaches as candidate tools for minimal residual disease (MRD) assessment and molecular surveillance.
Deep knowledge-driven multi-modal fusion for diagnosis and prognosis of SI-ARDS
Abstract Sepsis-Induced Acute Respiratory Distress Syndrome (SI-ARDS) presents significant diagnostic and prognostic challenges due to its complex clinical manifestations and high mortality rate. We developed a deep Knowledge-Driven multi-Modal Fusion (KDMF) framework for the accurate diagnosis and prognosis of SI-ARDS. The model leverages multi-modal data, including CT images, CT reports, and laboratory indicators, alongside a disease-specific knowledge graph.
Computer Science > Artificial Intelligence
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Urban shrinkage and habitat quality in the Beijing-Tianjin-Hebei urban agglomeration: a regional linkage perspective on coupling coordination and network optimization
Abstract Urban shrinkage leads to population loss, economic decline, and spatial contraction, thereby exerting significant effects on urban sustainable development and the ecological environment. This study focuses on the Beijing-Tianjin-Hebei urban agglomeration (BTH) and examines the coordinated development of urban shrinkage and habitat quality from a regional linkage perspective between 2010 and 2020.
Unraveling the Molecular Pathways of Insulin-Producing Cells Derived From Placenta Multipotent Stem Cells via Multi-Omics Analysis
J.Xu, X.Shen, Y.Gu, D. F.Lewis, D.Zoorob, and Y.Wang, “Unraveling the Molecular Pathways of Insulin-Producing Cells Derived From Placenta Multipotent Stem Cells via Multi-Omics Analysis.” PROTEOMICS (2026): e70120. https://doi.org/10.1002/pmic.70120 Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement All data associated with this study are present in the paper or the supplementary materials.
Multimodal contrastive prognostication framework for early neurological outcome prediction in post-cardiac arrest patients
Abstract Sudden cardiac arrest (SCA) remains a critical public health challenge with mortality rates close to 90%. Current prognostication methods commonly analyze data of individual modalities separately and delay assessment until 72 hours post-arrest, creating a critical gap in early decision-making.
Multimodal radiomics based on dynamic contrast-enhanced ultrasound for predicting cervical lymph node metastasis in papillary thyroid carcinoma with Hashimoto’s thyroiditis
Abstract Objective: This study aimed to develop and validate a multimodal predictive model by integrating radiomic features from B-mode ultrasound (BMUS) and dynamic contrast-enhanced ultrasound (DCE-US) parametric imaging, as well as clinical and conventional ultrasound features, for preoperative prediction of cervical lymph node metastasis (CLNM) in patients with Hashimoto’s thyroiditis (HT) complicated with papillary thyroid carcinoma (PTC).
A multi-scale perspective on the accessibility of public electric vehicle charging stations and community equity disparities
Abstract The accessibility of public electric vehicle charging stations (EVCS) is a critical factor in the widespread adoption of electric vehicles (EVs). Optimizing their spatial distribution to achieve equitable service coverage has become a vital task for promoting sustainable urban development.
Multidirectional lateral shearing random-step instantaneous phase-shifting interferometry for aspherical measurement
To further enhance measurement accuracy for aspheric surface wavefronts, a multi-directional lateral shearing instantaneous phase-shifting interferometry (MLSIPSI) method for aspheric surface testing is proposed by incorporating phase-shifting technology, and an MLSIPSI experimental system constructed. The experiment measured aspherical mirrors with asphericities of 4 and 10 µm, respectively, and compared the results with LUPHOSscan profilometer data.
Proteomic analysis of heparin amelioration of cardiac injury after CA-CPR in rats: an exploratory proteomic study
1 Introduction Cardiac arrest (CA) is one of the leading causes of death and disability worldwide (1). Although advances in cardiopulmonary resuscitation (CPR) techniques have significantly improved the success rate of return of spontaneous circulation (ROSC), many CA patients still die after ROSC due to myocardial dysfunction (2).
The Evolution and Integrated Systems of Microbatteries
Advances in microbatteries (MBs) technology drive miniaturization and on-chip integration, embedding energy storage directly within semiconductor substrates to deliver compact power solutions for portable electronics. This progress meets growing demands across applications such as Internet of Things (IoT) sensors and wearable devices.
Frontiers | Global burden and epidemiological trends of paediatric-onset multiple sclerosis: a cross-sectional analysis of the 2021 global burden of disease study
1Department of Neurology, Affiliated Changshu Hospital of Nantong University, Changshu, China 2Department of Neurology, Pukou Hospital of Chinese Medicine Affiliated to China Pharmaceutical University, Pukou, China Background: Paediatric-onset Multiple Sclerosis (POMS) is a rare autoimmune disorder of the central nervous system, primarily affecting children and adolescents, characterized by recurrent episodes of neurological impairment.
Dual‐Redox Active Sites Enable High Initial Coulombic Efficiency and Long Lifespan of Carbazole‐Based Cathodes for Lithium Dual‐Ion Batteries
Conflict of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adfm73368-sup-0001-SuppMat.docx28.5 MB Supporting Information References 1, , , , Nat. Mater. 2012, 11, 19. 2, , , , , , , , Adv. Mater. 2022, 34, 2200912. 3, , , , , , , , , , Adv. Mater. 2024, 36, 2312486. 4, , , , , Adv. Mater. 2025, 37, 2416661.
LGE gets Lloyd's Register approval for ecoCPTR® carbon capture system | Babcock - Marine sector posted on the topic | LinkedIn
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A Holistic Picture of the Phase Construction Process of O3‐Structured NaNi1/3Mn1/3Fe1/3O2 for Sodium‐Ion Batteries
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202505824-sup-0001-SuppMat.docx10.1 MB Supporting Information References 1, , , , , , , Angew. Chem. 2024, 136, 202409152. 2, , , , , , , , Adv. Funct. Mater. 2024, 34, 2315437. 3, , , , , , , , , Adv. Funct. Mater. 2023, 33, 2304617. 4, , , , , , , , , Adv. Funct. Mater. 2024, 34, 2400261. 5, , , , , , , , , , Adv. Mater. 2024, 36, 2306533. 6, , , , , , , , , , Nat. Commun. 2021, 12, 2256.
SNORA74A Drives Self‐Renewal of Liver Cancer Stem Cells and Hepatocarcinogenesis Through Activation of Notch3 Signaling
1 Introduction Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and the third leading cause of cancer-related deaths worldwide with a steadily increased incidence.[1] Despite advances in surgical resection, systemic therapies, and immunotherapies, the prognosis of HCC remains unsatisfactory due to high recurrence rates and heterogeneity.[2, 3] There is an urgent need to develop new therapeutic strategies based on a deeper understanding of the mechanisms underlying...
[2504.00977] Chinese Grammatical Error Correction: A Survey
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
3D nanoporous Cu-Ni column arrays with integrated NiS/CuS composites as anode for lithium-ion batteries: A reinforced buffer structure for high-performance electrodes
Over the past two decades, advancements in portable electronics and electric vehicles have been propelled by significant improvements to lithium-ion batteries (LIBs) in terms of energy density and cost along the battery value chain [1], [2], [3], [4].
An Ion Discharge-Driven Thruster Based on a Lithium Niobate Piezoelectric Transformer
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速评《美国优先投资政策备忘录》对中国生物医药行业的潜在影响
当地时间2025年2月21日，美国总统特朗普发布了一份名为《美国优先投资政策》（America First Investment Policy）的备忘录（“备忘录”）[2]，宣布将调整美国投资政策，重点加强对中美双向投资的限制。其中，备忘录提及可能针对医疗及生物技术领域采取限制措施。备忘录发布后，笔者陆陆续续收到了大量相关咨询。本文将探讨该备忘录对中国生物医药领域的潜在影响，做出风险提示并提供应对建议。 一、对中国生物医药领域的潜在影响 （一）中国赴美投资 在中国赴美投资方面，备忘录明确指出，特朗普政府将“利用所有必要的法律工具，包括美国外国投资委员会（CFIUS），限制与中国有关联的主体投资于美国技术、关键基础设施、医疗、农业、能源、原材料或其他战略领域……”[3]，其中，医疗领域投资被明确纳入限制范围，这意味着中国生物医药企业在美投资可能面临更严格的审查，进一步增加其进入美国市场的难度和不确定性。...
De novo biosynthesis of cannabinoid and its analogs in Yarrowia lipolytica
Abstract Cannabis sativa has long been a cornerstone of both medicinal and cultural practices, with its therapeutic use spanning over 2,700 years. Central to its therapeutic effects are cannabinoids, which interact with the endocannabinoid system to influence various physiological processes such as anxiety, pain, and inflammation. Despite its benefits, cannabinoid production faces challenges and scarcity from plant extraction.
Failure Mechanisms and Design Strategies for Low-Temperature Solid-State Metal Batteries
Failure Mechanisms and Design Strategies for Low-Temperature Solid-State Metal Batteries Solid-state metal batteries (SSMBs), with their high theoretical energy density and inherent safety advantages, are considered to be the ultimate choice for next-generation energy storage systems. Extensive experimental and theoretical research has highlighted the remarkable electrochemical performance of SSMBs under moderate and high temperature conditions.
Buoy and Winch Collaborative Control System Based on Deep Reinforcement Learning
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Optimizing Shoulder Joint Positioning During Video‐Assisted Thoracoscopic Surgery: A Prospective Study on Prevention of Postoperative Ipsilateral Shoulder Pain
1 Introduction Post-thoracotomy ipsilateral shoulder pain (ISP) emerges as a multifaceted and prevalent postoperative complication in thoracic surgery, affecting a substantial proportion of patients. The incidence of ISP, reported to range widely from 30% to 70%, significantly impacts patient recovery and overall quality of life [1-3]. The pain experienced by patients varies in intensity and duration, ranging from mild discomfort to severe, further complicating postoperative care.
Study on Fatigue Fracture Behavior of S32750 Duplex Stainless Steel at Different Solution Temperatures
1. Introduction The strength of duplex stainless steel is approximately twice that of austenitic stainless steel. Moreover, it exhibits superior toughness and ductility compared to ferritic stainless steel, maintaining good toughness even at temperatures as low as −40 °C. In this study, duplex stainless steel is chosen as the research focus due to its irreplaceable role in various industries, particularly marine engineering and the petrochemical sector.
Des responsables et des experts appellent à une construction de qualité des parcs nationaux
Des responsables et des experts chinois et étrangers ont appelé à une construction de qualité des parcs nationaux lors d'un symposium international organisé dans la province chinoise de Hainan (sud). Le Symposium international 2024 sur les parcs nationaux de forêts tropicales humides s'est ouvert jeudi dans le district autonome Li de Baisha, à Hainan, sur le thème "Conserver les forêts tropicales humides : coexistence harmonieuse avec la nature".
解读2024年版《赫尔辛基宣言》最新亮点 - 全球医学研究伦理准则系统性更新
2024年10月19日，第75届世界医学会全体大会审议通过了《世界医学协会赫尔辛基宣言 — 涉及人类受试者的医学研究伦理原则》（以下简称“《赫尔辛基宣言》”）的最新修订版本，本次修订对宣言带来了系统性更新。作为一份涉及人体医学研究的伦理原则声明，自1964年初次颁布以来，《赫尔辛基宣言》已历经多次修订。经过六十年的发展，《赫尔辛基宣言》不仅成为了国际社会中有关临床试验和参与者保护的核心文件，还被多个国家纳入本国法律体系，成为解决医学研究伦理问题的重要指南。本文将着重介绍《赫尔辛基宣言》的效力及2024年版较2013年版的主要修订内容，帮助业界更深刻地理解当前伦理标准的变化趋势，准确把握对参与者尊重和保护的核心要求，并应对未来可能出现的新挑战与风险。 一、《赫尔辛基宣言》的强制效力与更新的影响...
细胞与基因治疗领域又一利好：研究者发起的临床研究（IIT）管理办法正式落地
近日，国家卫生健康委员会（下称“国家卫健委”）、国家中医药局和国家疾控局三部委联合发布了《医疗卫生机构开展研究者发起的临床研究管理办法》（下称“《IIT管理办法》”），自2024年10月1日起正式施行。在此之前，国家卫健委曾发布过《医疗卫生机构开展研究者发起的临床研究管理办法（试行）》（下称“《试行稿》”）对IIT研究[1]进行监管，《试行稿》于2021年10月1日在北京、上海、广东、海南开展试行。试行期间，医疗卫生机构在开展IIT研究的实践中积累了较多经验，《试行稿》完成其使命，《IIT管理办法》正式落地。...
Ohmic Contact Formation to β-Ga2O3 Nanosheet Transistors with Ar-Containing Plasma Treatment
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A comparative study of esketamine-propofol and sufentanil-propofol for
Back to Journals » Drug Design, Development and Therapy » Volume 18 Authors Li N , Qi X, Bao J, Gu Y, Zhou X , Wang T, Jiang N, Wang Y, Ye Q Received 20 July 2024 Accepted for publication 18 November 2024 Published 25 November 2024 Volume 2024:18 Pages 5397—5407 DOI https://doi.org/10.2147/DDDT.S487872 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.
rGO/MWCNT-COOH-Modified Electrodes for the Detection of Trace Cd(II) and Zn(II) in Coastal Seawater
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User Scheduling and Path Planning for Reconfigurable Intelligent Surface Assisted MISO UAV Communication
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A liquid biopsy assay for the noninvasive detection of lymph node metastases in T1 lung adenocarcinoma
INTRODUCTION Lung cancer poses a serious threat to human health as one of the malignant tumors with the highest morbidity and mortality worldwide.1, 2 Non-small cell lung cancer comprises 85% of all lung cancer cases, with more than half of these cases presenting as lung adenocarcinoma.3 The early detection of lung cancer has significantly improved in recent years, thanks to the advances in screening methods and imaging technologies.
Study on the Effect of Microstructure and Inclusions on Corrosion Resistance of Low-N 25Cr-Type Duplex Stainless Steel via Additive Manufacturing
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ISAC towards 6G Satellite-Terrestrial Communications: Principles, Status, and Prospects
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Nomogram for predicting moderate-to-severe sleep-disordered breathing in patients with acute ischaemic stroke: a retrospective cohort study
Discussion In this retrospective cohort study, we developed and validated a nomogram that incorporates five clinical variables to assess the likelihood of moderate-to-severe SDB in mild AIS patients. Nomograms are widely used in research for risk prediction, calculating individual risk by considering relevant population-specific factors.10–12 Our results showed that the screening tool has good discrimination ability and a satisfactory goodness‐of‐fit.
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