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Yang-Liu Zhou on Muck Rack

Yang-Liu Zhou

As seen in: Nature
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Driver gene-based prognostic model benchmarked against machine learning survival models is associated with a CAF–TGFβ–EMT-like phenotype in hepatocellular carcinoma

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By Li Zhang, Tao Meng, Chao Yu, Longfei Dai, Jia Wang, Mingya Yang, Shuo Liu, Na Xu, Huan Zhou, Li-Xin Zhu, Zhen Zhang, Yang-Liu Zhou, Ruomu Ge
| Nature Verified
Abstract Hepatocellular carcinoma (HCC) is molecularly heterogeneous, limiting conventional prognostic tools. Whole-genome resequencing of six HCC cases was used only to filter candidates. Somatically mutated genes were intersected with HCC-annotated entries from five predefined driver resources, yielding 154 genes. DGPM-HCC, a 13-gene model summarized by TotalScore, was developed in 170 bulk transcriptome samples.
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