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Yangyingzi Xi on Muck Rack

Yangyingzi Xi

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Articles

CCDC120 phase separation contributes to desmosomal integrity and cardiac function

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By Hui Meng, Wei Zhao, Donghui Zhang, Rixu Cong, Tianning Wang, Yingchun Hu, Yonglu Tian, Xiaopeng Zou, Junlin Teng, Jianguo Chen, Ning Huang, Yangyingzi Xi, Xipan Han, Linwen Gong
| Nature Verified
Abstract Desmosomes are cell-cell adhesive junctions that provide structural integrity and mechanical resistance to tissues. Disruptions in desmosome organization lead to severe cardiac and dermatological disorders. Emerging evidence reveals that desmosomes exhibit dynamic behaviors during remodeling. However, the mechanisms that initiate and regulate these dynamics under physiological conditions, and their correlation with desmosome-related disorders remain elusive.
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