Yankey Yundung

You are already at the latest version Background/Objectives: Nuclear receptor corepressors NCOR1 and NCOR2 are key regulators of transcriptional repression, chromatin remodelling, and immunometabolic signalling. While NCOR1 has already been linked to vascular biology, its relevance in abdominal aortic aneurysm (AAA) remains unclear, particularly for NCOR2. This study aimed to investigate the expression, cellular localisation, and molecular interactions of NCOR1/2 in human AAA tissue.

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3.3. Stability of RNA over Time In our experimental approach, outlined below, the extent of RNA degradation in the study samples (Mu, HA, AAA, PAD)—all of which were incubated at 4 °C—was analysed in different protective solutions (CpS, PBS, RNAlater) at different time points (Figure 3, Figure 4 and Figure 5). The RINs of the muscle samples at time point 0 were 7.7 ± 0.6 (Figure 3A).