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Yaochang Yuan

As seen in: MDPI, Cell Reports
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Articles

Harnessing T-Cells for Enhanced Vaccine Development against Viral Infections

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By Zhen Zhuang, Yaochang Yuan, Zhao Chen, Jianfen Zhuo
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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A Bivalent Nanoparticle Vaccine Exhibits Potent Cross-protection against the Variants of SARS-CoV-2

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By Yaochang Yuan, Sun Yat-sen, Xiantao Zhang, Ran Chen
| Cell Reports Verified
Highlights - D614G/B.1.351-bivalent vaccine induces robust immune responses. - Bivalent vaccine protects mice from SARS-CoV-2 infection in a prime-boost manner. - A single-dose of bivalent vaccine shows superior protection during B.1.351 infection. - A third-dose strategy elicits nAbs against SARS-CoV-2 variants in rhesus macaques. Summary The inoculation of vaccines against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is undergoing worldwide.
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